David J Robbins Selected Research

8-oxodGTPase

1/2020	The Existence of MTH1-independent 8-oxodGTPase Activity in Cancer Cells as a Compensatory Mechanism against On-target Effects of MTH1 Inhibitors.
11/2019	Increased MTH1-specific 8-oxodGTPase activity is a hallmark of cancer in colon, lung and pancreatic tissue.

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David J Robbins Research Topics

Disease

17	Neoplasms (Cancer) 01/2021 - 03/2006
6	Carcinogenesis 01/2021 - 10/2006
5	Adenocarcinoma 01/2021 - 03/2007
4	Neoplasm Metastasis (Metastasis) 01/2021 - 03/2007
3	Birth Weight (Birth Weights) 11/2019 - 07/2013
3	Colorectal Neoplasms (Colorectal Cancer) 11/2019 - 02/2016
3	Medulloblastoma 01/2019 - 09/2014
2	Lung Neoplasms (Lung Cancer) 11/2012 - 03/2007
1	Multiple Myeloma 01/2021
1	Myelodysplastic Syndromes (Myelodysplastic Syndrome) 01/2021
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 12/2019
1	Precancerous Conditions 12/2019
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 11/2019
1	Dysbiosis 01/2019
1	Inflammation (Inflammations) 01/2019
1	Disease Progression 01/2019
1	Glioma (Gliomas) 02/2016
1	Glioblastoma (Glioblastoma Multiforme) 03/2015
1	Basal Cell Carcinoma (Rodent Ulcer) 09/2014
1	Adenoma (Adenomas) 01/2014
1	Malignant Mesothelioma 01/2014
1	Enterobiasis 01/2014
1	Intestinal Polyposis (Polyposis, Intestinal) 01/2014
1	Disease Susceptibility (Diathesis) 07/2013
1	Carcinoma (Carcinomatosis) 09/2012
1	Urinary Bladder Neoplasms (Bladder Cancer) 03/2010
1	Adenocarcinoma of Lung 03/2007
1	Ectrodactyly 06/2005
1	Hypertrophy 04/2002

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 01/2021 - 10/2006
5	ArsenicIBA 11/2019 - 03/2010
4	HhAntag691IBA 08/2020 - 01/2014
4	Pharmaceutical PreparationsIBA 01/2019 - 01/2014
2	GANT 61IBA 08/2020 - 01/2014
2	GuanineIBA 01/2020 - 11/2019
2	8-oxodGTPaseIBA 01/2020 - 11/2019
2	Adenosine Triphosphate (ATP)IBA 01/2020 - 11/2019
2	pyrvinium (Vankin)FDA Link 12/2019 - 01/2014
2	4- (N- methyl- N- (4- (trifluoromethyl)phenyl)sulfamoyl) benzoic acidIBA 01/2019 - 06/2017
2	Hedgehog ProteinsIBA 12/2014 - 03/2006
2	Biomarkers (Surrogate Marker)IBA 09/2014 - 01/2014
2	Cyclin EIBA 11/2012 - 03/2007
1	RNA Polymerase II (RNA Polymerase B)IBA 01/2021
1	Immunomodulating AgentsIBA 01/2021
1	Phosphotransferases (Kinase)IBA 01/2021
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2021
1	Casein Kinases (Casein Kinase)IBA 08/2020
1	8-oxodeoxyguanosine triphosphateIBA 11/2019
1	Opioid Analgesics (Opioids)IBA 01/2019
1	Volatile Fatty AcidsIBA 01/2019
1	Histone Deacetylases (Histone Deacetylase)IBA 01/2019
1	Morphine (MS Contin)FDA LinkGeneric 01/2019
1	Calcibiotic Root Canal SealerIBA 06/2017
1	Drug CombinationsIBA 03/2015
1	GSK1210151AIBA 12/2014
1	Smoothened ReceptorIBA 12/2014
1	Gamma Secretase Inhibitors and ModulatorsIBA 11/2014
1	Phenobarbital (Luminal)FDA Link 11/2014
1	DNA (Deoxyribonucleic Acid)IBA 09/2014
1	RetinoidsIBA 04/2014
1	Arsenic Trioxide (Trisenox)FDA Link 01/2014
1	Itraconazole (Sporanox)FDA LinkGeneric 01/2014
1	Phospholipases (Phospholipase)IBA 07/2013
1	cyclopamineIBA 11/2012
1	LigandsIBA 09/2012
1	CarcinogensIBA 03/2010
1	TeratogensIBA 06/2005
1	Parathyroid Hormone-Related ProteinIBA 04/2002

Therapy/Procedure

4	Therapeutics 01/2021 - 03/2015
1	Drug Therapy (Chemotherapy) 11/2014
1	Oral Administration 01/2014